The excess sodium concentration in blood has worse effects almost all over the body, but it has the worst effects on the brain cells. The neurologic impact of hypernatremia is the most severe symptom of sodium toxicity, which are as follows:
Alteration in mental status
Neuromuscular issues such as irritability
Focal neurological deficits
The death rate of this neurological impact of sodium toxicity is high as 50% of the total patients. These episodes result from shrinkage caused in the brain cells due to the transfer of water from the intracellular matrix to the extracellular matrix due to increased ionic concentration in the extracellular fluid. The other effects of the hypernatremia that is sodium toxicity are as follows;
The decrease in the contractility of the left ventricle of the heart
Disturbance in the utilization of the glucose even if the digestion is proper
Cramps in muscles
The Treatment Approach of Sodium Toxicity
The treatment of sodium toxicity is entirely focused on decreasing the elevated level of sodium present in the plasma up to the normal level or in the normal range of the sodium level. The process should be in optimum intensity because a sudden rise or fall in any ionic concentration will lead to serious complications. The management of the toxicity should focus upon the following important factors:
The rate of the ionic correction should be optimum
Selecting an appropriate method to do the same
Never ignore the predisposing conditions of the patient, such as diabetes
The most important measure that should be taken is the oral or nasogastric administration of water to compensate for the water loss that has taken place inside the body. For correct compensation for the water loss, the total body water should be calculated. It is calculated by multiplying the bodyweight of the person by 0.6. The reason behind this is that two-third of the bodyweight of a person is the normal weight of water. This Total body weight should be 50% for the females and 60% for the males. Apply the corrective measures to maintain the levels in their appropriate range.
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